If you still have problems run SpyBot Search and Destroy. Same sort of thing as AdAware but different technology so sometimes you need to run both to get everything :)

The other great thing to be released is the Beta version of the Google Toolbar. Install it and then go to options and check the pop up killer. There is some debate over it killing legitimate popups but I've had no conclusive evidence and it's great.

You know you need a clean up when you are visiting friends and the 6 year olds go to the Lego site and get porn popups!